A. The problem:
Toolbox Client starts, displays splash screen, but the application window disappears immediately after that, leaving a process in the Task Manager.
At the same time Toolbox Server display the following error: System.TypeInitializationException: The type initializer for '<Module>' threw an exception. ---> System.BadImageFormatException: Could not load file or assembly (see Figure 1)
As a result, the Toolbox server is running only.
B. Description of the problem:
Windows antivirus application will sometime have false positives where it will mark Toolbox as a virus.
C. How to solve the issue
To fix that you need to allow Toolbox from the “Virus & threat protection”, following the steps outlined below.
Step 1: Click on “Virus & threat protection” in the Windows search (Figure 2)
Step 2: Click on “Protection history” (Figure 3)
Step 3: Click on the last blocked application (Figure 4)
Step 4: Click on “Actions” and then “Allow” (Figure 5)
Step 5: You can now start the QSAR Toolbox.